Catalog Products
ADP-Ribosylation Factors (ARF)
Adrenomedullin Peptides
Agouti Related Peptides
Amylin Peptides
Amyloid Peptides
Angiotensins and Related Peptides
Annexin
Anti-Inflammatory Peptides
Antimicrobial and Related Peptides
Antioxidant Peptides
Apelin Peptides
Apolipoprotein Peptides
Apoptosis Peptides
Arg-Phe-Amide RFamide Related Peptides
Bacterial Peptides
Basic Fibroblast Growth Factor (bFGF)
Bcl / BAD Peptides
Bombesins
Bradykinins
C-Peptides
C3a Peptides
Calcitonin Related Peptides
Cancer Research Peptides
Cardiac Peptides
CART (Cocaine- and Amphetamine-Regulated Transcript) Peptides
Casomorphin Peptides
Caspase Related Peptides
CEF Control Peptides
Cell Adhesion Peptides
Cell Permeable Peptides (CPP) / Drug Delivery Peptides
Chemotaxis Peptides
Cholecystokinin-Pancreozymin Peptides
ClearPoint™-Heavy Isotope Labeled and Related Peptides
Corticotropin Related Peptides
Cyclic Peptides
Cytochromes and Related Peptides
Defensins
Deltorphin Peptides
Dynorphin Peptides
Endorphin Peptides
Endothelins
Enkephalins
Enzyme Substrates and Inhibitors
Exendins
Extracellular Matrix
Fibrinogen and Related Peptides
Fibronectin Fragments
Fluorescent Labeled Peptides
FRET Peptides
Galanins
Gastric Inhibitory Peptides (GIPs)
Gastrins
Ghrelins and Obestatins
Glucagon-Like Peptides
Glycopeptides
GPCR Peptide Ligands
Growth Factors
Growth Hormone Related Peptides
Hepatitis C Virus (HCV) Related Peptides
Histones
Guanylins
HIV Related Peptides
Hydrocarbon-Stapled Peptides
Integrins
Ion Channel Peptides
Kinases/Phosphatase Substrates
Luteinizing Hormone-Releasing Hormones and Related Peptides
MAPS Peptides
Matrix Metalloproteinases (MMPs)
Melan-A and Mucin Related Peptides
Melanocyte Stimulating Hormones and Analogs
MHC related
Microbial Peptides
Milk Peptides
Myelin Oligodendrocyte Glycoprotein (MOG)/Myelin Basic Proteins (MBP)
Myosin
Natriuretic Peptides
Neurokinins
Neuromedins
Neuropeptide Y and Analogs
Neuropeptides
Neurotensins and Related Peptides
NF-kB/Transcription Factors Related Peptides
Opioid Related Peptides
Orexins
Osteocalcin Fragments
OVA Peptides
Oxytocins, Vasopressins, and Related Peptides
p53 Peptides
Pancreatic Polypeptides
Parathyroid Hormones and Related Peptides
Peptide Aminoluciferin Custom Synthesis For Bioluminescent Assays
Peptide Standards
Peptide YY and Analogs
Peptidoglycan Peptides
Phagocytosis
Phosphopeptides
Phytochelatins
Pituitary Adenylate Cyclase Activating Peptides (PACAPS)
Prion Protein (PrP) Fragments
Prolactin Releasing Peptides
Protease Inhibitors
Protein Phosphorylation Related Peptides
Proteolipid Proteins (PLPs)
QA-GSH
Renin
Retinoid Binding Protein
RGD Peptides
Saposin Related Peptides
Secretins
Selectin Related Peptides
Signal Transduction Peptides
Somatostatins
Substance P and Analogs
Tag Peptides
Tau Peptides
Temporins
Thrombin Related Peptides
Thrombospondins
Thyrotropin Releasing Hormones and Related Peptides
Toxins
Tubulin Peptides
Urotensin related peptides
Vasoactive Intestinal Peptides (VIPs)
Viral Peptides
您的位置:主页 > Catalog Products > 目录肽 > 研发肽 > Caspase Related Peptides
  Product  Caspase 8 Substrate 1
  chromogenicAc - IETD - pNA
  CAS  CMV pp65 (495 - 503)NLVPMVATV
  Size  5 mg
  Catalog #  25258-5
  US$  105
  Hits  

Description

pNA (4-nitroaniline)-derived caspase substrates are widely used for the colorimetric detection of various caspase activities. Cleavage of pNA peptides by caspases generates pNA that is monitored colorimetrically at ~405 nm. pNA has maximum absorption around 408 nm.

Caspase-8 substrate with Km = 66 uM; Substrate for granzyme B

Detailed Information Datasheet
Storage -20°C desiccated and protected from light
References Grutter MG (2000). Caspases: key players in programmed cell death. Curr Opin Struct Biol 10, 649-55; Gastman BR (2001). Apoptosis and its clinical impact. Head Neck 23, 409-25; Grutter MG (2000). Caspases: key players in programmed cell death. Curr Opin Struct Biol 10, 649-55; Stennicke HR and Salvesen GS (1999). Catalytic properties of the caspases. Cell Death Differ 6, 1054-9; Stennicke HR and Salvesen GS (1998). Properties of the caspases. Biochim Biophys Acta 1387, 17-31; Thornberry NA and Lazebnik Y (1998). Caspases: enemies within. Science 281, 1312-6; Talanian RV, et al. (1997). Substrate specificities of caspase family proteases. J Biol Chem 272, 9677-82; Fassy F, et al. (1998). Enzymatic activity of two caspases related to interleukin-1beta-converting enzyme. Eur J Biochem 253, 76-83; Datta R, et al. (1996). Activation of the CPP32 protease in apoptosis induced by 1-?-D-arabinofuranosylcytosine and other DNA-damaging agents. Blood 88, 1936-43; Koeplinger KA, et al. (2000). Caspase 8: an efficient method for large-scale autoactivation of recombinant procaspase 8 by matrix adsorption and characterization of the active enzyme. Protein Expr Purif 18, 378-87.
Molecular Weight 638.6
Product Citations Rocha, R. et al. (2011). Arsenic and fluoride induce neural progenitor cell apoptosis. Toxicol Lett10.1016/j.toxlet.2011.03.023.
Shao, R. et al. (2005). E1A sensitizes cancer cells to TRAIL-induced apoptosis through enhancement of caspase activation. Mol Cancer Res 3, 219.
Tang, C-HA. et al. (2005). Synergism of Rana catesbeiana ribonuclease and IFN-γ triggers distinct death machineries in different human cancer cells. FEBS Lett 579, 265.


版权所有 成都凯捷生物医药科技发展有限公司 All rights reserved.
电话:028-88268610,88203630,88203631,88203633 Email:sales@kjpep.com 蜀ICP备19030014号-1