EDANS is one of the most popular donors for developing FRET-based nucleic acid probes and protease substrates. EDANS is often paired with DABCYL or DABSYL in FRET-based probes. Its fluorescence is environment-sensitive.
Becker BF, et al. (2002). Application of peptides containing the cleavage sequence of pro-TNFa in assessing TACE activity of whole cells. Biol Chem 383, 1821-6; Wang GT, et al. (1993). A continuous fluorescence assay of renin activity. Anal Biochem 210, 351-9.
Molecular Weight
266.32
Molecular Formula
C12H14N2O3S
Spectral Properties
Abs/Em = 335/493 nm
Solvent System
water or DMSO
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Material Safety Data Sheets (MSDS)