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  Product  Boc - D - propargylglycine
  
  CAS  
  Size  5 g
  Catalog #  64514-5
  US$  583
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Description

An unusual amino acid used in Solid Phase Peptide Synthesis (SPPS) as: A) a precursor to the tritium-induced Norvaline peptides,1 B) in the synthesis of branched peptides using a palladium-catalyzed coupling reaction,2 and C) as a reagent in the dual-catalyst Sonogashira coupling reaction.3

Detailed Information Material Safety Data Sheets (MSDS)
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Storage 4°C
References 1. Eberle, A. N.; Zeller, A. Tritiation of Peptides to High Specific Radioactivity. Part 1. Synthesis and Biological Properties of [13-(3H4)Norvaline]-α-MSH and of [2,23-Bis((3H2)tyrosine)]ACTH(1-24). Helvetica Chim. Acta. 1985 (68) 1880-1892. 
2. Crisp, G. T.; Robertson, T. A. Palladium-catalyzed coupling of a propargylglycinededrivative. Tetrahedron. 1992 (48) 3239-3250. 
3. Sonogashira, K.; Tohda, Y.; Haghiara, N. A convenient synthesis of acetylenes: catalytic substitutions of acetylenic hydrogen with bromoalkenes, iodoarenes, and bromopyridines.Tetrahedron Lett.,1975 (16) 4467-4470.
Molecular Weight 213.23
Molecular Formula C10 H15 NO4


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